Portrait Professor Andrea Hoffmann

Science for Patients –
Biohybrid Implants

My dream was and remains to this day, to make an impact on finding novel solutions for improving treatments for patients and to extend our knowledge as a researcher.
To do so, I have tackled different medical topics.
Today, I am working in optimizing implants for patients and in understanding the basic biology of body´s own stem cells.
My current position as university professor started from a research unit professorship sponsored by the German Research Foundation (DFG).
Find my complete CV here.

On the left you see me with Teruko Tamura´s Tree (donation by Dr. Patrik Schadzek). I am glad to welcome you!

Biohybrid Implants

  • Graded Implants
  • Body´s Own Stem Cells
  • Immune Cells (Macrophages)

Our Research – a Brief Introduction

Current Address:
Clinic of Orthopedic Surgery / NIFE
Stadtfelddamm 34
30625 Hannover, Germany

The Team

Our work is interdisciplinary.
My team brings in their expertise from different aspects within the life sciences.
In addition, we constantly have students who perform their bachelor´s or master´s theses in our lab.

Portrait Kirsten Elger

Kirsten Elger

Medical-technical laboratory assistant

Kirsten is well versed in flow cytometry, cloning, and cell culture. Additionally, she takes care of our budget and is coordination assistant within the DFG-funded research unit RU 2180.

Anika Hamm

Biological-technical assistent

Anika has been a member of my group since my beginning at MHH. She is experienced in cell culture including isolation of stem cells under hypoxic conditions, molecular biology, and protein biochemistry like co-immunoprecipitation of proteins.

Portrait Yvonne Roger

Yvonne Roger

PhD, diploma in biology

Yvonne is the most experienced scientist of my group. She established herself as an integral and indispensable researcher within RU 2180 and focuses on the cytocompatibility of different biomaterials as well as the differentiation of stem cells under different conditions.

Portrait Patrik Schadzek

Patrik Schadzek

Dr. rer. nat., M. Sc. in life science

Patrik compares functions of stem cells from patients with bone sarcomas and osteoarthritis. Since last year he is member of a project within the collaborative research center SIIRI which investigates cellular and molecular aspects of aseptic loosening of orthopedic implants.

Photo of the group in NIFE including students.
Photo of the group in NIFE including students.

The Voluntary Team Members –
Invaluable Background Support

Did you wonder about my logo?
Actually, my cockatiels have inspired my logo: the black circle as their eye, and a stylish feather tuft in the colour of their feathers.
The feather tuft reflects the different scientific topics that I addressed in my career up to the present day: kidney / proteinuria, cerebrospinal fluid / blood-brain barrier, heart / cardiac allograft vasculopathy, musculoskeletal system / stem cells.

Voluntary Team Members
The first two diploma students under my practical supervision.
The first two diploma students under my practical supervision.

Former Lab Members

Imke Bargen, Tobias Braun, Johannes Brendel, Jasemin Brikey, Dr. Laura Burmeister, Janina Conradi, Anastasia Dielmann, Heike Dornhoff, Peter Eberle, Michel Evert, Jennifer Friesen, Dr. Nelson Gekara, Henning Hartwig, Mike Hasenberg, Claudia Heidorn, Karolina Heinrichs, Nils Hottenbacher, Hanna Humbach, Dr. Nico Jäschke, Marcel Jaron, Caroline Jerrentrup, Felix Keil, Adrian Kordes, Carlotta Kornblum, Mareike Kubinski, Nurdan Kudu, Maike Kuhn, Fabienne Libuda, Sarah Lindenlaub, Yvonne Medler, Sabrina Meine, Rieke Moritz, Susanne Nagel, Dr. Sandra Noack, Malin Peter, Svenja Rieke, Nathalie Rosner, Isabel Ramón Roth, Dr. Luisa Schäck, Janett Schaper-Rinkel, Franziska Scholl, Justin-John Schrader, Jennifer Schulze, Yasmin Schwier, Dr. Virginia Seiffart, Dr. Sandra Shahab-Osterloh, Meike Simann, Yan Thorsting, Isabelle Trieu, Dr. Ramona Weist, Patrick Wellbrock, Sabrina Wiechmann, Dr. Andreas Winkel, Claas Wodarczyk


Here you will find our latest scientific achievements, general news or job offers.

(please do not apply without job posting)

  • Cartilage


    Cartilage hardly regenerates due to a low number of blood vessels and nerves. We currently plan a project in which we are seeking for innovative solutions, based on novel biomaterials and novel small-molecule drugs, together with colleagues. Artwork by Dr. Yvonne Roger.

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  • Project funding by Erwin Röver-Stiftung: ‘A biomarker for aseptic implant loosening?’

    Project funding by Erwin Röver-Stiftung: ‘A biomarker for aseptic implant loosening?’

    In aseptic loosening of arthoplasties (hip, knee), inflammation – not caused by external triggers such as bacteria – leads to dissolution of the bone and progressive implant loosening. These processes are the main cause of follow-up surgery. The triggering factors of the inflammation have not yet been clarified. While abrasion or corrosion (‘particle disease’) of…

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  • Thank you to our donors

    Thank you to our donors

    Thank you to all donors of the tissue samples from which we perform our analyses! Without your tissue donations, our patient-centred biomedical research would not be possible. The photo shows a bone marrow aspiration from the iliac crest. Photo by Nina Friese.

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  • How to obtain mesenchymal stem cells from bone marrow?

    How to obtain mesenchymal stem cells from bone marrow?

    In October 2023, scientists from the institute of Cell Biology and Biophysics, Leibniz University, from the institute of Micro Production Technology, Leibniz University, and from the institute of Experimental Infection Research, TWINCORE worked with Anika in our lab to isolate human mesenchymal stem cells from bone marrow, see photo. For more information, also watch our…

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