Six genes allow to differentiate healthy from diseased tendon. Patrik Schadzek, Kirsten Elger, Peter Paes, Andrea Hoffmann*, Alexander Derksen*

New data on gene expressions allow diagnosis

It is often difficult to distinguish healthy from diseased tendons and to choose the right patient treatment.

We aim to identify a pattern of gene markers that might allow such differentiation. To do so, we have isolated RNA from different tendons from more than 80 human patients and subjected them to RNA-sequencing. We pinpointed a pattern of six genes that allow assignment of tendons with unknown status to either cohort, see Figure.