Graded Implants for Tendon-Bone Connections

DFG-Funded Research Unit RU 2180

Tissue transitions have a particular importance in the musculoskeletal system. They are frequently impaired by pathological processes. Current treatment modalities are hardly able to restore original functionality and largely fail within the long run. Implants might provide solutions to this challenge but implants for tissue transitions are still lacking.

We are currently working on a novel bioinspired solution within RU 2180. The annual retreats of this DFG-funded collaborative project which expires in 2023 took place in Wennigsen, see photo. The PI is the spokeswoman of the project.

Natural tissue transitions have multiple gradients: gradients of structure, composition, biomechanics, and ensuing functionality. The aim of the DFG-funded research unit RU 2180 “Graded Implants for Tendon-Bone Connections” is to demonstrate the feasibility and model production of a novel biodegradable and multi-graded implant for future use at the tendon-bone tissue transition of the rotator cuff. RU 2180 spans disciplines from engineering, natural and life sciences, and medicine: Our annual meetings were held in Johanniterhaus Kloster Wennigsen, see photo, and the final colloquium was held in “Pferdestall”, Hannover.